Blastocyst Culture

At Simply Fertility we offer embryo transfer 7 days a week. Embryos are usually transferred anytime between day 2 and day 5. Blastocyst transfer is a selection tool which helps us to identify the strongest embryo/s for transfer and is a good technique to use where more good quality embryos have developed by day 3 than are needed for transfer.

The Scientists at Simply Fertility are pioneers in the development of Blastocyst transfer programs in the UK with over 20 years experience.

Time Lapse Incubation - The EmbryoScope™

We are entrusted with the most precious gift in the world, your future baby, which is why we have developed the most advanced laboratory.

We are delighted to offer a new and revolutionary treatment which some studies have shown an increase in IVF pregnancy rates.   EmbryoScope™ Treatment  enables our embryologists to not only nurture your embryos but select the most viable ones for transfer, giving you the best possible chance of IVF success.

EMBRYOSCOPE™ Embryo development time-lapse imaging
A new time-lapse technology called the Embryoscope™ involves culturing embryos in an incubator equipped with a special microscope, camera and computer. Available since 2011 it has already led to the birth of thousands of healthy babies. Each individual embryo is imaged separately and monitored every 15 minutes allowing subtle changes in development to be detected. This allows selection of embryos with the highest pregnancy potential – so-called morphokinetics.

Up to 70% of embryos appear normal when observed on a daily basis using older incubation systems yet do not go on to give successful pregnancy after transfer. The ability to more accurately select an embryo capable of pregnancy on the basis of the time-lapse imaging is an exciting development. It is also thought that embryos identified in this way are less likely to lead to early pregnancy loss than other systems and preliminary results are excellent.

Identifies your most viable embryos

Embryonic development is dynamic. By continuously monitoring every stage of development,  the  embryologists   are   able to select the best, most viable embryos for transferring, at the right time.

Maintains genuine undisturbed cultures

Unlike traditional incubation techniques which routinely require embryos to  be  removed for assessment under a microscope, the EmbryoScope’s internal camera records development whilst maintaining optimal culture conditions. Embryos remain undisturbed.

Very first images of your future baby

This pioneering technique provides precious, real time video imagery of every moment from the beginning of life for you to cherish.  You will be given a memory stick containing a video of the transferred embryo.

EmbryoGlue™

Hyaluranon is a naturally occurring substance present in follicles, tubes and cavity of the womb. Its effect is to make the fluid in these areas more viscous (sticky) and to encourage implantation of the embryo

EmbryoGlue can be used in an IVF/ICSI cycle. The embryo is placed in this special media just before transfer. There have been studies that have shown that this can help with implantation. There are other studies that show that there is no benefit from using EmbryoGlue

The HFEA advise there is no conclusive evidence to suggest that Embryo glue increases pregnancy rates during IVF treatment. For more information please see the HFEA advice at:
www.hfea.gov.uk/treatments/explore-all-treatments/ treatment-add-ons/
Please speak to a member of staff if you would like to discuss this further.

Endometrial Scratch

At Simply Fertility we offer a procedure called an ‘Endometrial Scratch’. Some studies have suggested that the endometrial scratch may improve implantation rates, however other studies have found that there is no difference. Embryo implantation into the womb may fail due to poor embryo quality or abnormal embryo genetics. It can also often fail due to poor ‘endometrial receptivity’. This is where the lining of the womb is not favourable for the embryo to implant.

What is an endometrial scratch procedure?

The endometrial scratch is a straightforward out-patient procedure which is relatively painless (similar to a cervical smear test). The procedure involves “scratching” the endometrial lining of the womb with a very small catheter (plastic tube) prior to an attempt to get pregnant.

How could the procedure help with implantation?

The procedure is thought to increase the immune system cells and therefore the growth factors at the site of the endometrial scratch. This is believed to make the womb lining more receptive to embryo implantation. Studies have suggested that implantation rates may be twice as high in patients who have an endometrial scratch before attempting to get pregnant.

When should an endometrial scratch be done?

It is recommended that the endometrial scratch is performed in the cycle before you start stimulation medication. Ideally the procedure should be done between days 17 and 21 of your menstrual cycle.

How is the procedure performed?

You will attend the clinic with a semi-full bladder (drink 300ml of water 1 hour prior to the procedure, and do not empty your bladder during this time). A very small catheter will then be inserted through the cervix into the womb. This catheter will be used to scratch 4 areas on the womb lining. You may experience slight discomfort as the catheter is being passed into the womb.

What should I expect after the procedure?

After the procedure, a small amount of vaginal spotting or bleeding is not unusual. You can commence an IVF cycle as normal the following month.

Evidence

The HFEA advise there is no conclusive evidence to suggest the endometrial scratch increases pregnancy rates during IVF treatment. For more information please see the HFEA advice at:
www.hfea.gov.uk/treatments/explore-all-treatments/ treatment-add-ons/
Please speak to a member of staff if you would like to discuss this further.

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Monday 29 April

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